Sequential Oxygenation Index and Organ Dysfunction Assessment within the First 3 Days of Mechanical Ventilation Predict the Outcome of Adult Patients with Severe Acute Respiratory Failure
Table 8
Day 1 and day 3 respiratory and ventilator parameters of patients with different weaning outcomes#.
Day 1 and Day 3 Respiratory and ventilator parameters
Characteristics
Weaning success
Weaning failure
value
Fi Day1
0.55 (0.2)
0.46 (0.17)
0.1
Pa Day 1 (mmHg)
129.11 (79.84)
119.5 (54.74)
0.69
PEEP* Day 1 (mmHg)
5.41 (1.33)
5.0 (1.10)
0.27
mPaw* Day 1 (mmHg)
12.0 (3.22)
11.56 (3.14)
0.64
PaO2/FiO2 Day 1 (mmHg)
259.02 (180.78)
284.36 (184.45)
0.63
OI* Day 1
6.99 (5.15)
5.46 (3.4)
0.27
FiO2 day 3
0.38 (0.08)
0.4 (0.14)
0.57
PaO2 Day 3 (mmHg)
114.63 (24.8)
112.64 (26.09)
0.79
PEEP Day 3 (cmH2O)
5.41 (1.33)
5.0 (1.1)
0.43
mPaw day 3 (cmH2O)
10.37 (2.44)
11.19 (2.14)
0.24
PaO2/FiO2 Day 3 (mmHg)
313.94 (76.81)
313.02 (112.25)
0.97
OI Day 3 (cmH2O/mmHg)
3.67 (2.03)
4.39 (2.82)
0.27
OI change from day 1 to day 3 (cmH2O/mmHg)
−3.32 (4.46)
−1.06 (1.97)
0.008
*FiO2: fraction inspired oxygen, mPaw: mean airway pressure, OI: oxygenation index, PaO2: arterial oxygen tension, PEEP: positive end expiratory pressure.
#Continuous variables were analyzed by Student’s t-test or Mann-Whitney U test. Variables are expressed as mean (standard deviation).
