Clinical Study
Reactive Oxygen Species Production in Peripheral Blood Neutrophils of Obstructive Sleep Apnea Patients
Table 1
Characteristics of the controls and the obstructive sleep apnea patients.
| | Characteristic | Control group () | OSA group () | value |
| | Age (years) | 44 (32–46) | 43 (35–50) | >0.05 | | Epworth sleepiness scale | 9 (9–13) | 5.5 (5–11) | 0.39 | | Body mass index (kg/m2) | 25.3 (23.7–27.8) | 30.6 (28.4–36.6) | <0.001 | | Waist circumference (cm) | 90 (87–93) | 106 (98–116) | <0.001 | | Polysomnographic parameters: | | | | | Apnea/hypopnea index (events/h) | 2.6 (2.1–3.4) | 29.9 (15.8–70.2) | <0.001 | | Arousal index (events/h) | 19.1 (14.2–24.1) | 39.3 (21.6–58.4) | 0.001 | | Oxygen desaturation index (events/h) | 2.9 (1.0–3.8) | 42.9 (12.8–74.2) | <0.001 | | Average SpO2 (%) | 97 (96-97) | 94 (92–95) | <0.001 | | Total sleep time SpO2 < 90% (%) | 0 (0–0.2) | 4.4 (0.4–24.3) | <0.001 | | Blood parameters: | | | | | Total cholesterol (mmol/L) | 4.99 (4.88–5.62) | 5.68 (4.94–6.48) | >0.05 | | High-density lipids (mmol/L) | 1.16 (1.02–1.51) | 0.91 (0.79–1.04) | 0.01 | | Low-density lipids (mmol/L) | 3.24 (3.07–3.61) | 3.27 (3.15–4.21) | >0.05 | | Triglycerides (mmol/L) | 0.92 (0.79–1.11) | 1.73 (0.94–2.57) | 0.03 | | Glucose (mmol/L) | 5.0 (4.29–5.33) | 5.59 (5.31–5.93) | 0.01 | | ROS (MFI) | 28.29 (16.5–58.1) | 58.44 (29.9–108.4) | 0.02 |
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Data is presented as median (25th and 75th percentiles). Mann-Whitney test. Statistically significant differences are bolded.
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