Research Article

Anti-Inflammatory Property of the Ethanol Extract of the Root and Rhizome of Pogostemon cablin (Blanco) Benth

Table 1

Effect of ERP on carrageenan-induced the levels of TNF-α, IL-6 and IL-1β in mouse paw edema.

GroupsTNF-α (pg/mg protein)IL-6 (ng/mg protein)IL-1β (ng/mg protein)

Control5.62 ± 1.7228.66 ± 3.8522.36 ± 2.30
Carrageenan61.11 ± 5.22#188.47 ± 15.69#136.41 ± 11.01#
ERP (120 mg/kg)39.85 ± 4.89*136.35 ± 13.14*72.19 ± 8.84*
ERP (240 mg/kg)33.00 ± 2.79**124.76 ± 14.80*66.10 ± 6.52**
ERP (480 mg/kg)28.44 ± 4.98**105.18 ± 16.37**59.67 ± 5.38**
Indomethacin (10 mg/kg)24.13 ± 3.17**95.20 ± 10.51**52.84 ± 7.12**

Data represented the mean ± S.E.M. ( ). #P < 0.01 compared to the control group; *P < 0.05 and **P < 0.01 compared to the carrageenan-control group.