The Scientific World Journal / 2013 / Article / Tab 2

Research Article

Evaluation and Optimization of Downstream Process Parameters for Extraction of Betulinic Acid from the Bark of Ziziphus jujubae L.

Table 2

Design matrix for the optimization of extraction parameters for maximum recovery of betulinic acid as response.

RunTypeFactorsBA yield (% w/w)
pHTime (min) Temp. (°C) ObservedPredicted

1Center6.503.5045.000.210.24
2Center6.503.5045.000.210.24
7Center6.503.5045.000.210.24
8Center6.503.5045.000.210.24
16Center6.503.5045.000.350.37
19Center6.503.5045.000.210.24
3Axial6.503.5070.230.40.44
6Axial0.613.5045.000.060.07
15Axial12.393.5045.000.10.12
17Axial6.503.5019.770.080.09
18Axial6.506.0245.000.210.24
20Axial6.500.9845.000.070.09
4Factorial10.005.0060.000.250.26
5Factorial3.005.0030.000.060.09
9Factorial10.005.0030.000.120.14
10Factorial3.002.0060.000.240.26
11Factorial10.002.0060.000.290.31
12Factorial3.005.0060.000.330.34
13Factorial3.002.0030.000.040.06
14Factorial10.002.0030.000.050.04

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