Transient Hemodynamic Changes upon Changing a BCPA into a TCPC in Staged Fontan Operation: A Computational Model Study

Table 2

Simulated hemodynamic variables for the BCPA circulation and the TCPC circulation under resting conditions compared with the measured data.

	Glenn (mea.)	Glenn (sim.)	TCPC (sim.)
m𝑃svc (mmHg)	14.0±2.0 [31]; 10.0 [18]	10.0	8.5
m𝑃ivc (mmHg)	5.4±3.2 [32]	5.3	8.0
m𝑃pa (mmHg)	12.3±3.1 [33]; 9.0 [18]	9.0	7.8
m𝑃la (mmHg)	5.0 [18]	5.0	3.4
m𝑃art (mmHg)	72.0 [18]; 73±10 [32]	72.1	45.6
SV (mL)	20.1*	20.1	11.7
EDV (mL)	32.4*	32.5	19.4
EF (%)	62±7 [31]	61.9	60.2
m𝑄pul (mL/s)	15.6 [18]	15.7	17.4
CO (mL/s)	31.2±7.2 [31]; 28.9 [18]	30.0	17.4

Notation of hemodynamic variables: m𝑃_svc, m𝑃_ivc, m𝑃_pa, m𝑃_la, and m𝑃_art represent the mean pressure in the superior vena cava, the inferior vena cava, the pulmonary artery, the left atrium, and the systemic arteries, respectively; SV, EDV, and EF refer, respectively, to the stroke volume, the end-diastolic volume, and ejection fraction of the left ventricle; m𝑄_pul denotes the mean blood flow rate through the pulmonary circulation; and CO is cardiac output. The data marked with “*” were derived from CO and EF by assuming a cardiac duration of 0.67 s.