The Scientific World Journal / 2013 / Article / Tab 5

Review Article

Multiple Myeloma and Kidney Disease

Table 5

Classification of CKD based on presence or absence of systemic disease and location within the kidney of pathologic-anatomic findings [33].

Examples of systemic diseases affecting the kidneyExamples of primary kidney diseases

Glomerular diseasesDiabetes, systemic autoimmune diseases, systemic infections, drugs, and neoplasia (including amyloidosis)Diffuse, focal, or crescentic proliferative GN, focal and segmental glomerulosclerosis, membranous nephropathy, and minimal change disease
Tubulointerstitial diseasesSystemic infections, autoimmune, sarcoidosis, drugs, urate, and environmental toxins,
Multiple myeloma
Urinary-tract infections, stones, and obstruction
Vascular diseasesAtherosclerosis, hypertension, ischemia, cholesterol emboli, systemic vasculitis, thrombotic microangiopathy, and systemic sclerosisANCA-associated renal limited vasculitis and fibromuscular dysplasia
Cystic and congenital diseasesPolycystic kidney disease, Alport syndrome, and Fabry diseaseRenal dysplasia, medullary cystic disease, and podocytopathies

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