Involvement of MAPKs and PLC Pathways in Modulation of Pacemaking Activity by So-Cheong-Ryong-Tang in Interstitial Cells of Cajal from Murine Small Intestine
Figure 3
Effects of GDP-β-S in the pipette on SCRT-induced pacemaker potentials in cultured ICCs of murine small intestine. (a) SCRT (30 mg/mL) induced membrane depolarizations on ICCs. (b) Pacemaker potentials of ICCs exposed to SCRT (30 mg/mL) in the presence of GDP-β-S (1 mM) in the pipette. Under these conditions, SCRT (30 mg/mL) caused membrane depolarization. (c) Responses to SCRT in the presence of GDP-β-S in the pipette are summarized in (b). Bars represent mean values ± SEs. . Significantly different from untreated controls. CTRL: Control.
