Involvement of MAPKs and PLC Pathways in Modulation of Pacemaking  Activity by So-Cheong-Ryong-Tang in Interstitial Cells of Cajal from Murine Small Intestine

<table>Effects of SCRT on phospholipase C inhibitors in cultured ICCs. (a) SCRT (30 mg/mL) induced membrane depolarizations on ICCs. (b) U-73122 (5 <i>μ</i>M), a phospholipase C inhibitor, abolished the generation of pacemaker potentials. U-73122 blocked the SCRT-induced (30 mg/mL) membrane depolarizations. (c) The application of U-73343 (5 <i>μ</i>M) did not show any influence on the generation of pacemaker currents. Also, U-73343 did not block the SCRT-induced (30 mg/mL) membrane depolarizations. (d) The responses to SCRT in phospholipase C inhibitors are summarized in (d). Bars represent mean values ± SEs. <svg height="13.95" id="M35" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 73.300003 13.95" width="73.300003" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>. Significantly different from untreated controls. CTRL: Control.</table>

The Scientific World Journal

fig5

Figure 5

Figure 5: Involvement of MAPKs and PLC Pathways in Modulation of Pacemaking  Activity by So-Cheong-Ryong-Tang in Interstitial Cells of Cajal from Murine Small Intestine 

Figure 5 | Involvement of MAPKs and PLC Pathways in Modulation of Pacemaking  Activity by So-Cheong-Ryong-Tang in Interstitial Cells of Cajal from Murine Small Intestine 