The Scientific World Journal

Research Article

Association of Interleukin-6 Gene Promoter Polymorphism with Coronary Artery Disease in Pakistani Families

Table 2

IL-6-174G>C genotype and allele frequencies of study population .
 Patients ( )Control ( ) value
IL-6-174G>C genotype   
 GG 18 (20.4%) 38 (43.2%)
 GC 11 (12.4%) 14 (16%)
 CC 7 (8.0%) — 
IL-6-174G>C allele frequencies   
 G 47 (65.3%) 90 (86.5%) (C versus G allele)
 C25 (34.7%) 14 (13.5%) OR = 3.4, 95% CI = 1.53–7.70
Values are given in percentage.
a value was calculated by chi-square test.
b value was calculated by the Fisher exact test. (OR: odds ratio for C and T allele frequencies in all subjects; CI: 95% confidence interval).