Glutathione Redox System in β-Thalassemia/Hb E Patients

Table 1

Hematological parameters of normal and 𝛽-thalassemia/Hb E subjects (mean ± SEM).

Subjects	Hematological data
	Hb	WBC	RBC	MCV	MCH	MCHC	Platelet	Reticulocyte
	(g/L)	(×10^9 cells/L)	(×10^12 cells/L)	(fL)	(pg)	(g/L)	(×10^9 cells/L)	(%)
Normal control (𝑛=27)	143.6±3.0	6.2±0.3	4.9±0.1	88.4±0.5	28.6±1.0	334.7±0.2	251.8±8.7	1.1±0.1
β-thalassemia/Hb E (𝑛=25)	71.6±2.7	30.9±10.1	3.8±0.2	60.2±1.7	19.0±0.5	316.5±0.4	359.0±50.6	6.4±1.6
𝑃 value	<0.001	0.015	<0.001	<0.001	<0.001	<0.001	0.035	<0.001
Splenectomized (𝑛=8)	70.6±6.3	79.8±24.4	3.5±0.4	67.8±2.6	20.2±0.9	298.5±0.5	656.6±76.2	14.1±3.9
Nonsplenectomized (𝑛=17)	72.0±2.8	7.9±0.7	3.9±0.1	56.6±1.4	18.4±0.5	324.9±3.2	214.3±18.9	2.7±0.3
𝑃 value	0.817	<0.001	0.314	<0.001	0.062	<0.001	<0.001	<0.001

Hb: hemoglobin; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; MCV: mean corpuscular volume; RBC: red blood cells; WBC: white blood cells.