Intrahost Diversity of Feline Coronavirus: A Consensus between the Circulating Virulent/Avirulent Strains and the Internal Mutation Hypotheses?

Table 2

Histopathological analysis and results of FCoV mRNA RT-PCR in diseased cats with FIP.

Cat (𝑛=8)	Histopathological findings	Positive samples for mRNA FCoV
Cat 6	Pyogranulomas in lung, kidneys, cerebrum, and cerebellum; Mild-to-moderate, subacute, multifocal fibrinous pleuritis; Vasculitis in heart, lung, omentum, kidneys, cerebrum, and cerebellum	Cerebrum,; cerebellum,; lung,; thymus,; spleen,; stomach,; mesenteric lymph node,; kidneys,; aqueous humour, and; faeces
Cat 7	Pyogranulomas in liver, kidneys, cerebrum, and cerebellum; Vasculitis in cerebrum	Cerebellum,; large intestine, and; large intestine content
Cat 8	Severe, subacute, diffuse fibrinous pleuritis and peritonitis	Lung,; thoracic lymph node,; thymus,; liver,; spleen,; stomach,; mesenteric lymph node,; peripancreatic lymph node,; kidneys,; large and small intestines,; small intestine content,; urinary bladder, and; abdominal effusion
Cat 9	Diffuse, severe, nonsuppurative meningoencephalitis	Aqueous humour right eye,; large intestine, and; large intestine content
Cat 10	Moderate, subacute, diffuse fibrinous pleuritis	Mesenteric lymph node,; large and small intestines contents, and; abdominal effusion
Cat 11	Subacute, multifocal fibrinous peritonitis; Moderate, diffuse interstitial pneumonia; Pyogranulomas in kidneys (with bacteria) and liver	Cerebrum,; aqueous humour left eye,; mesenteric lymph node, and; large intestine
Cat 12	Subacute, focally extensive fibrinous pleuritis; Pyogranulomas in kidneys	Cerebrum,; cerebellum,; aqueous humour left eye, and; thoracic effusion
Cat 13	Moderate, multifocal granulomatous pleuritis; Severe, granulomatous, interstitial nephritis, associated with coalescing areas of necrosis	Cerebrum,; aqueous humour left eye,; lung,; thoracic effusion,; mesenteric lymph node,; large and small intestines contents,; kidneys, and; abdominal effusion