Clinical Study
DNA Damage Sensor γ-H2AX Is Increased in Preneoplastic Lesions of Hepatocellular Carcinoma
Table 2
Associations of γ-H2AX with clinicopathological features in HCC.
| Clinicopathological variables | γ-H2AX immunoreactivity | | Low () | High () | value* |
| Age (year) | | | | 50 | 2 | 4 | | ≥50 | 16 | 36 | 0.613 | Gender | | | | male | 15 | 34 | | female | 3 | 6 | 0.576 | Tumor size (cm) | | | | 3 | 5 | 11 | | ≥3 | 13 | 29 | 0.609 | Intrahepatic metastasis | | | | − | 14 | 30 | | + | 4 | 10 | 0.550 | Venous invasion | | | | − | 16 | 37 | | + | 2 | 3 | 0.497 | Histological grade† | | | | I/II | 10 | 35 | | III/IV | 8 | 5 | 0.011* |
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Histological grade was assessed according to the Edmondson-Steiner grade. value of Chi2 test.
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