Genetic Markers Associated to Dyslipidemia in HIV-Infected Individuals on HAART
Table 2
Characteristics of the study participants.
All study participants
PI-sparing ART
PI-based ART
value
Demographic
Age, years
Male sex, (%)
341 (55.5)
179 (58)
162 (54)
0.348*
Ethnicity, (%)
Euro-Brazilians
349 (57)
166 (48)
183 (60)
0.094*
Afro-Brazilians
265 (43)
145 (47)
120 (40)
Physical activity, (%)
156 (25)
74 (24)
82 (27)
0.389*
Cigarette smoking, (%)
186 (30)
103 (33)
83 (28)
0.153*
Clinical
CD4, cells/uL
Therapy time (months)
0.00
Lipid-lowering drugs, (%)
105 (17)
42 (14)
63 (21)
0.021*
Metabolic
Triglycerides, mg/dL
0.00
Total cholesterol, mg/dL
HDL-C, mg/dL
0.00
LDL-C, mg/dL
Dyslipidemia, (%)
455 (74)
215 (69)
240 (79)
0.006*
Hypertriglyceridemia
293 (49)
122 (40)
171 (59)
<0.001*
Hypercholesterolemia
245 (41)
118 (39)
127 (44)
0.267*
Low HDL-C
185 (31)
74 (24)
111 (38)
<0.001*
Data presented as mean SD or number of patients (%). PI: protease inhibitors; ART: antiretroviral therapy; HDL-C: high-density lipoprotein; LDL-C: low-density lipoprotein. ¥ value expressed with tests performed with ln-transformed variable. Student -test for independent samples.
*
-Test with Yates correction. Student -test for independent samples with ln-transformed variable.