Inhibitory Effect of r-Hirudin Variant III on Streptozotocin-Induced Diabetic Cataracts in Rats

Table 4

The effect of rHV3 eye drops on the activities of MDA, SOD, and GSH-Px in the lens on diabetic cataract in Sprague-Dawley rats (𝑥±𝑠).

Group	𝑛	MDA (nMol/mg prot)	SOD (U/mg prot)	GSH-Px (U/mg prot)
A	16	0.441±0.07^∗∗	10.07±1.77^∗∗##	8.55±1.83^∗∗
B	13	0.686±0.16	4.75±1.38	4.03±1.31
C	13	0.513±0.20	6.92±1.52^∗∗	5.18±1.77
D	14	0.482±0.21^∗	7.84±1.29^∗∗	7.84±1.81^∗∗
E	15	0.456±0.14^∗∗	8.21±1.31^∗∗	9.73±2.50^∗∗##
F	12	0.478±0.15^∗	7.08±1.17^∗∗	6.82±1.41^∗∗

 ^∗𝑃<0.05, ^∗∗𝑃<0.01 versus group B (model, treated with eye drops vehicle).
 ^#𝑃<0.05, ^##𝑃<0.01 versus group F (pirenoxine treated).