PLZF Expression during Colorectal Cancer Development and in Normal Colorectal Mucosa according to Body Size, as Marker of Colorectal Cancer Risk

Figure 2

Confocal immunofluorescence staining of colorectal carcinogenesis. Examples of confocal analysis of cryosections of normal colorectal mucosa (NM), aberrant crypt foci (ACF), and colorectal carcinoma (CRC), labelled by DAPI (blue), PLZF (green), CD2 (magenta), and CD56 (red). (a)–(c): PLZF with CD2 in NM (a), ACF (b), and CRC (c). (d)–(f): PLZF and CD56 in NM (d), ACF (e), and CRC (f). (g)–(i): immunostaining of PLZF alone in NM (g), ACF (h), and CRC (i). Scale bar = 80 μm.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)