A Comparative Genomic Study in Schizophrenic and in Bipolar Disorder Patients, Based on Microarray Expression Profiling Meta-Analysis

Table 5

The fourteen common DE genes in schizophrenic and BD samples compared to control samples derived from the first study.

Gene symbol	FC (log2)	FC (log2)	Gene title
	SZ versus control	BP versus control
SLC25A1	−0.624219	−0.627028	“Solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1"
HTR2C	−0.511652	−0.515884	5-hydroxytryptamine (serotonin) receptor 2C
SYP	−0.506666	−0.644315	Synaptophysin
SERINC5	−0.476598	−0.564567	Serine incorporator 5
CGRRF1	0.388505	0.443519	Cell growth regulator with ring finger domain 1
SF3B1	0.434178	0.435295	Splicing factor 3b, subunit 1, 155 kDa
ADD2	0.476098	0.529755	Adducin 2 (beta)
GRK5	0.554659	−0.593328	G protein-coupled receptor kinase 5
UCHL3	0.587522	0.701958	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
DARC	0.642385	0.498777	Duffy blood group, chemokine receptor
SEPT11	0.651131	−0.551204	septin 11
MT1X	0.754667	0.966154	Metallothionein 1X
CEBPD	0.774212	0.726239	CCAAT/enhancer binding protein (C/EBP), delta
LGALS3	0.892986	0.636527	Lectin, galactoside-binding, soluble, 3

Downregulation of genes in each disease state compared with controls is represented with negative FC values (fold decrease) and upregulation with positive FC values. Most statistically significant genes, common in SZ and BD, are differentiated in similar way.