The Ethanol Extract of the Inner Bark of Caesalpinia pyramidalis (Tul.) Reduces Urinary Bladder Damage during Cyclophosphamide-Induced Cystitis in Rats

Figure 1

The ethanol extract of Caesalpinia pyramidalis (EECp) decreases the myeloperoxidase (MPO) activity in bladder of rats during cyclophosphamide-induced cystitis. Animals were treated with EECp (100–400 mg/kg, p.o.), vehicle, or mesna (40 mg/kg, i.p.) and injected with cyclophosphamide (200 mg/kg, i.p.). After 24 h, the MPO activity was determined in urinary bladder homogenate and was expressed as units (U) of MPO/mg of tissue. ^###𝑃<0.001 versus vehicle + saline; ^∗𝑃<0.05 or ^∗∗∗𝑃<0.001 versus vehicle + cyclophosphamide.