One-Pot Synthesis of 2′-Aminobenzothiazolo-Arylmethyl-2-Naphthols Catalyzed by NBS under Solvent-Free Conditions

Table 1

The synthesis of 2^′-aminobenzothiazolo-phenyl-2-naphthol in various conditions.

Entry	Solvent	NBS; (mol%)	Temperature; (°C)	Time; (min)	Yield; (%)
1	Water	10	25	90	59
2	Water	10	60	60	88
3	Ethanol-water	10	25	60	56
4	Ethanol-water	10	60	30	85
5	Neat	0	60	60	0
6	Neat	2	60	30	73
7	Neat	5	60	20	89
8	Neat	10	25	60	65
9	Neat	10	60	10	94
10	Neat	15	60	10	92
11	Neat	20	60	10	92