Research Article

Oncogene- and Oxidative Stress-Induced Cellular Senescence Shows Distinct Expression Patterns of Proinflammatory Cytokines in Vascular Endothelial Cells

Figure 1

SA-β-Gal staining of HUVECs. HUVECs were infected with AdRas12V for 1 week to induce senescence or with AdGFP as the negative control. Senescence was also induced in HUVECs treated with 100 μmol/L H2O2 for 1 hr. Arrows indicate large and round-shaped senescent cells, and arrowheads indicate flat or spindle-shaped senescent cells.
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