Oncogene- and Oxidative Stress-Induced Cellular Senescence Shows Distinct Expression Patterns of Proinflammatory Cytokines in Vascular Endothelial Cells
Figure 1
SA-β-Gal staining of HUVECs. HUVECs were infected with AdRas12V for 1 week to induce senescence or with AdGFP as the negative control. Senescence was also induced in HUVECs treated with 100 μmol/L H2O2 for 1 hr. Arrows indicate large and round-shaped senescent cells, and arrowheads indicate flat or spindle-shaped senescent cells.