18F-Fluorothymidine-Pet Imaging of Glioblastoma Multiforme: Effects of Radiation Therapy on Radiotracer Uptake and Molecular Biomarker Patterns
Figure 4
FLT-PET imaging demonstrates RT-induced changes in tumor cores. (a) 18F-FLT-PET of bilateral flank tumors prior to unilateral 16 Gy RT. Note the similar pattern of radiotracer uptake bilaterally in coronal and axial views (white arrows). 3D CT/bone imaging for flank surface anatomy is shown. (b) 18F-FLT-PET of bilateral flank tumors 2 weeks after unilateral 16 Gy RT. Unique variations in radiotracer uptake are seen. Note decreased radiotracer in control tumor core (white arrows); uniform uptake in RT tumors (yellow arrows). 3D CT/bone imaging for flank surface anatomy is shown.
