Cardiac Safety of Diclofenac at a Single Dose in Ram

Table 3

The effect of diclofenac (2.5 mg/kg, IM) on hemogram parameters in rams (mean ± SEM).

Parameters	0 (control) hour	6 hours	% alteration	𝑃 values
WBC (×10^9/L)	7.29±1.14	5.81±0.98	−20.30	𝑃<0.006
Lymphocyte %	64.7±2.28	53.2±4.14	−17.8	𝑃<0.041
Monocyte %	3.46±0.46	3.30±0.32	−4.62	𝑃>0.05
Granulocyte %	31.8±1.99	42.5±3.98	+33.6	𝑃<0.032
RBC (×10^12/L)	13.0±0.28	14.0±0.26	+7.69	𝑃<0.019
Thrombocyte (×10^9/L)	355±74.0	436±44.9	+22.8	𝑃>0.05
Hematocrit %	36.8±1.03	38.7±1.70	+5.16	𝑃>0.05
Hemoglobin (g/L)	11.7±0.33	12.2±0.35	+4.27	𝑃>0.05

WBC: white blood cell; RBC: red blood cell.