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The Scientific World Journal
Volume 2013, Article ID 821650, 6 pages
Review Article

Treatment of Periprosthetic Infections: An Economic Analysis

1Hospital St Agustín and School of Medicine, 33400 Oviedo, Spain
2Orthopaedic Surgery and Traumatology Institute, 08009 Barcelona, Spain
3Hospital of Cartagena, 30203 Murcia, Spain
4Hospital of Cabueñes and School of Medicine, 33394 Oviedo, Spain
5Hospital Costa del Sol, 29603 Marbella, Spain
6Hospital Sabogal, Colina 1081, Bellavista-Callao, Peru

Received 26 February 2013; Accepted 30 April 2013

Academic Editors: S.-Y. Kim, W. Klauser, M. S. Lee, and C. S. Mow

Copyright © 2013 Daniel Hernández-Vaquero et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This review summarizes the existing economic literature, assesses the value of current data, and presents procedures that are the less costly and more effective options for the treatment of periprosthetic infections of knee and hip. Optimizing antibiotic use in the prevention and treatment of periprosthetic infection, combined with systemic and behavioral changes in the operating room, the detection and treatment of high-risk patient groups, as well as the rational management of the existing infection by using the different procedures according to each particular case, could allow for improved outcomes and lead to the highest quality of life for patients and the lowest economic impact. Nevertheless, the costeffectiveness of different interventions to treat periprosthetic infections remains unclear.