A Noninvasive Neuroprosthesis Augments Hand Grasp Force in Individuals with Cervical Spinal Cord Injury: The Functional and Therapeutic Effects

Table 3

Summary of change scores of the 27 patients completing the intervention period: immediate (AM₀-AN₀), therapeutic (AN₁-AN₀), training (AM₁-AM₀), and combined effect (AM₁-AN₀) with interquartile range. Number of positive change scores and number of clinically relevant improvements are listed in the last two rows together with their 95% confidence intervals.

Change score	AM0-AN0	AN1-AN0	AM1-AM0	AM1-AN0
Median [IQR]	2 [−1,4]	1 [0,2]	2 [0,4]	4 [2,6]
(Wilcoxon—𝑃)	(𝑃<0.02)	(𝑃<0.01)	(𝑃<0.0001)	(𝑃<0.0001)
Count of positive change scores	17	15	18	24
95% CI	[44%, 78%]	[37%, 72%]	[48%, 81%]	[72%, 96%]
Count exceeding 5.7 points	4	0	2	8
95% CI	[6%, 33%]	[0%, 13%]	[4%, 28%]	[16%, 49%]