Research Article
Sulfonic Acid Functionalized Nano-γ-Al2O3: A New, Efficient, and Reusable Catalyst for Synthesis of 3-Substituted-2H-1,4-Benzothiazines
Table 2
Solvent optimization for the synthesis of 3-phenyl-2H-1,4-benzothiazinea.
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Reaction conditions: o-aminothiophenol (1 mmol), 2-bromo-1-phenyl-ethanone (1 mmol); sulfonic acid functionalized nano-γ-Al2O3 (50 mg); reflux. Isolated yield. |