Isotretinoin Oil-Based Capsule Formulation Optimization

Table 3

Optimal regression equation for each response variable.

	𝑌10min	𝑌30min	𝑌60min	𝑌90min
𝑏1(𝑋1)	−100.04	922.67	436.82	272.32
𝑏2(𝑋2)	−6.45	−21.46	16.45	51.87
𝑏3(𝑋3)	7.67	20.39	57.42	82.03
𝑏12(𝑋1𝑋2)	207.53	−809.95	−250.14	−104.70
𝑏13(𝑋1𝑋3)	89.44	−1138.72	−633.23	−285.57
𝑏23(𝑋2𝑋3)	64.65	249.62	251.99	157.24
𝐹	17909.89	499.69	4092.21	264.78
𝑃	0.0057	0.0340	0.0119	0.0466
C.V.	0.52	2.88	0.52	0.88
𝑅^2	1.0000	0.9996	1.0000	0.9992
Adjusted 𝑅^2	0.9999	0.9976	0.9997	0.9955