Phenotypes and Genotypes of Patients with Pantothenate Kinase-Associated Neurodegeneration in Asian and Caucasian Populations: 2 Cases and Literature Review

Table 2

Clinical findings in Asian patients: classic versus atypical.

	Classic	Atypical	𝑃 value*
	𝑁=9	𝑁=12
Age at onset (years)	6.7 (2–10)	30.7 (17–51)	<0.05
Dysarthria	89%	42%
Gait disturbance	89%	50%
Dystonia	78%	75%
General dystonia	67%	0%	<0.05
Cranial dystonia	22%	50%
Segmental dystonia	0%	67%	<0.05
Dysphagia	56%	8%	<0.05
Pyramidal signs	56%	17%
Mental impairment	44%	8%
Limb chorea	44%	8%
Tremors	22%	83%	<0.05
Parkinsonism	11%	42%
Psychiatric symptoms	0%	0%

∗Blank indicates it does not reach statistical significance (𝑃≥0.05).