Efficiency of pH-Sensitive Fusogenic Polymer-Modified Liposomes as a Vaccine Carrier
Figure 3
Th1 (IFN-γ) and Th2 (IL-4) cytokine secretion by spleen cells from mice after intraperitoneal administration of OVA-containing SucPG-modified liposomes. Spleen cells were harvested on day 7 after secondary immunization and cultured with OVA for 5 days. Subsequently, culture supernatants were collected for the analysis of cytokine production by ELISA. Values represent the mean ± SEM of cytokine production by spleen cells of mice in each group (nontreated control mice (Control) and OVA-containing SucPG-modified liposome-immunized mice (Group III)). (a) IFN-γ. (b) IL-4.
