Effect of Polyunsaturated Fatty Acids on Homocysteine Metabolism through Regulating the Gene Expressions Involved in Methionine Metabolism

Table 3

Changes of biochemical measurements in the rats after the supplementation.

	CC	18:1	22:6𝑛-3	20:5𝑛-3	18:3𝑛-3	18:2𝑛-6	CLA	SO
LDL-C, mmol/L	0.22±0.12	0.21±0.11	0.21±0.12	0.18±0.10^∗	0.20±0.23	0.26±0.11	0.19±0.12	0.28±0.13
TG, mmol/L	0.91±0.76	1.07±0.70	1.07±0.75	1.08±0.74	1.04±0.87	0.73±0.71^∗	1.06±0.73	0.86±0.84
HDL-C, mmol/L	0.98±0.69	0.98±0.63	1.00±0.68	0.94±0.67	1.11±0.80^∗	0.98±0.64	0.86±0.67	0.96±0.76
TC, mmol/L	1.82±0.78	1.83±0.72	1.84±0.77	1.72±0.75^∗	1.94±0.89	1.82±0.73	1.65±0.75	1.80±0.86
Glucose, mmol/L	5.98±2.18	6.01±2.01	5.49±2.16^∗	4.94±2.14^∗	4.82±2.27^∗	5.44±2.03	6.19±2.11	5.15±2.40^∗
Uric acid, µmol/L	49.02±8.68	44.88±7.99	39.34±8.59^∗	43.00±8.57	52.12±8.71	48.50±8.08	44.64±8.39	43.92±9.55
ALT,U/L	55.80±9.12	61.20±8.39	56.57±9.03	49.80±9.01	57.60±9.12	58.80±8.49	58.60±8.82	47.40±10.03^∗
AST, U/L	184.20±26.74	231.40±21.60	168.86±26.48	159.40±26.45^∗	181.20±26.56	192.40±24.89	190.00±25.86	140.80±29.41^∗
Creatinine, µmol/L	63.00±10.21	61.78±9.39	63.21±10.11	59.30±10.09^∗	62.90±10.20	59.78±9.51	57.34±9.87^∗	56.58±11.23^∗
BUN, mmol/L	5.95±2.19	6.33±2.01	6.50±2.17	5.81±2.15	5.85±2.26	6.08±2.04	5.83±2.12	5.52±2.41^∗
Alb, g/L	45.34±9.19	46.12±8.45	45.70±9.10	45.72±9.08	46.22±9.21	45.56±8.56	45.64±8.89	44.60±10.11
Glob, g/L	24.50±7.12	23.20±6.55	27.30±7.05	22.24±7.03^∗	28.26±7.14	24.00±6.63	23.96±6.89	24.54±7.83
A : G	1.87±0.78	2.00±0.72	1.69±0.77	2.06±0.75	1.67±0.89	1.91±0.73	1.91±0.75	1.84±0.86
TP, g/L	69.84±9.91	69.32±9.12	73.00±9.81^∗	67.96±9.79	74.48±9.90^∗	69.56±9.23	69.60±9.58	69.14±10.90
VitaminB12, ng/mL	688±78	691±89	690±101	695±70	691±84	690±120	690±97	688±89
Folate, pmol/L	26.8±7.9	26.3±6.1	27.0±5.8	26.9±6.8	27.1±7.3	26.2±5.7	26.0±8.5	26.5±7.1

Sample size in each group: 𝑛=10, data was expressed as mean ± SD.
*indicates significant difference when compared with 18:1 group.
CC: control group; CLA: conjugated linoleic acid; SO: stearolic acid; TC: total cholesterol; TG: total triglyceride; HDL-C: high density cholesterol; LDL-C: low density cholesterol; A : G: Alb : Glob; ALT: alanine transaminase; AST: aspartate aminotransferase; TP: total protein; BUN: blood urea nitrogen.