Comparison of Nasal Epithelial Smoking-Induced Gene Expression on Affymetrix Exon 1.0 and Gene 1.0 ST Arrays
Smoking-induced differentially expressed genes using a Student’s t-test (a) within the Human Exon 1.0 ST array and (b) within the Human Gene 1.0 ST. (c) Correlation between smoking-induced gene-expression differences (fold change) of the Exon and Gene ST arrays for 16,482 best matched gene-level probe sets.
(a) Human Exon 1.0 ST array
(b) Human Gene 1.0 ST array
(c) Fold changes between the log2 mean values for 5 current smokers (C) and 5 never smokers (N) were calculated independently for the Exon and Gene ST arrays for 16,482 best matched genes. This fold change correlation () is higher than the correlation between the Exon and U133A arrays ()