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The Scientific World Journal
Volume 2013, Article ID 956837, 4 pages
http://dx.doi.org/10.1155/2013/956837
Clinical Study

Thyroid Autoimmunity and Behçet’s Disease: Is There a Significant Association?

1Department of Dermatology, Haydarpaşa Numune Training and Research Hospital, 34668 İstanbul, Turkey
2Department of Dermatology, Faculty of Medicine, Bezmialem Vakıf University, İstanbul, Turkey
3Biochemistry Laboratory, Haydarpaşa Numune Training and Research Hospital, 34668 İstanbul, Turkey
4Department of General Medicine, Haydarpaşa Numune Training and Research Hospital, 34668 İstanbul, Turkey

Received 18 December 2012; Accepted 8 January 2013

Academic Editors: A. Ishida-Yamamoto, C. Sitaru, and G. A. Vena

Copyright © 2013 Filiz Cebeci et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Behcet’s disease (BD) could be regarded as an autoimmune disease in many aspects. Autoimmune thyroid disease (ATD) is frequently accompanied by other various autoimmune diseases. Nevertheless, there is not still enough data showing the association between BD and ATD. In addition, no controlled study is present in the PubMed, which evaluates thyroidal autoimmunity using antithyroid peroxidase antibody in a large series of patients with BD. Methods. We aimed to investigate the frequency of ATD in patients with BD. The study included 124 patients with BD and 99 age- and sex-matched healthy volunteers. Results. Autoimmune thyroiditis was noted in 21 cases (16.9%) with BD. In the control group, 22 cases (22.22%) were diagnosed as autoimmune thyroiditis. There was no difference between the groups in respect to thyroid autoantibodies ( ). There were no statistically significant differences between baseline TSH levels of the BD patients and of the controls ( ). Statistically, the mean serum free T4 levels of the patients with BD were higher than those of the controls ( ). Conclusions. No association could be found between BD and ATD. Therefore, it is not of significance to investigate thyroid autoimmunity in BD.