Molecular Imaging of Experimental Abdominal Aortic Aneurysms

Figure 4

Near-infrared fluorescence (NIRF) image of both angiotensin II-induced and elastase-induced aneurysms. (a) Control apolipoprotein-E deficient mouse aorta after injection of MMPSense 680. (b) Infrarenal aortic aneurysm induced via elastase infusion. (c) Suprarenal aortic aneurysm induced via angiotensin II infusion. (d) Dorsal and (e) ventral NIRF images of angiotensin II-induced abdominal aortic aneurysms showing asymmetric probe accumulation, suggestive of regional differences in protease activation and inflammation. Figure adapted from [77].