The Scientific World Journal / 2013 / Article / Fig 2

Review Article

Promising New Treatments for Psoriasis

Figure 2

Schematic representation of the mechanism of action of the small-molecule inhibitors. Jak: janus kinase; STAT: signal transducing proteins and activator of transcription; STAT-P: phosphorylated STAT (active); PDE 4: phosphodiesterase 4; NF-KB: nuclear factor kappaB; PKC: protein kinases C; DAG: diacylglycerol; cAMP: cyclic adenosine monophosphate; AMP: adenosine monophosphate.

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