Table of Contents Author Guidelines Submit a Manuscript
The Scientific World Journal
Volume 2014, Article ID 102736, 13 pages
http://dx.doi.org/10.1155/2014/102736
Review Article

Can Vascular Endothelial Growth Factor and Microvessel Density Be Used as Prognostic Biomarkers for Colorectal Cancer? A Systematic Review and Meta-Analysis

Department of Epidemiology, Public Health College, Harbin Medical University, 157 Baojian Street, Nangang District, Harbin, Heilongjiang 150081, China

Received 11 November 2013; Accepted 29 January 2014; Published 27 March 2014

Academic Editors: E. Z. Dajani and C. Tosetti

Copyright © 2014 Yibaina Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [20 citations]

The following is the list of published articles that have cited the current article.

  • Derek J. Erstad, Gerald Tumusiime, and James C. Cusack, “Prognostic and Predictive Biomarkers in Colorectal Cancer: Implications for the Clinical Surgeon,” Annals of Surgical Oncology, 2015. View at Publisher · View at Google Scholar
  • Qiao Zhou, Wei Guo, Cong Long, Heng Zhou, and Xiao-Ping Sun, “Effect of heat shock protein 70 inhibitor PES on NF-κB signal pathway of human gastric cancer BGC cells,” Tumor, vol. 35, no. 3, pp. 246–252, 2015. View at Publisher · View at Google Scholar
  • Marcin Bobiński, Wiesława Bednarek, Justyna Szumiło, Marek Cybulski, Grzegorz Polak, and Jan Kotarski, “Microvessels Density in Uterine Leiomyosarcoma,” BioMed Research International, vol. 2015, pp. 1–5, 2015. View at Publisher · View at Google Scholar
  • Gibbons, Rogers, Winter, Heeney, Lugli, Puppa, and Sheahan, “Systematic review and meta-analysis of the impact of tumour budding in colorectal cancer,” British Journal of Cancer, vol. 115, no. 7, pp. 831–840, 2016. View at Publisher · View at Google Scholar
  • Michael Bramble, Colin J. Rees, Michael Gill, Clare E. Parker, Sarah L. Perry, Sarah Mills, D. Michael Bradburn, Elizabeth Walsh, Mark A. Hull, Roisin Bevan, and Yvonne Bury, “Are there biological differences between screen-detected and interval colorectal cancers in the English Bowel Cancer Screening Programme?,” British Journal of Cancer, vol. 115, no. 2, pp. 261–265, 2016. View at Publisher · View at Google Scholar
  • Amalia Azzariti, Anna Elisa Quatrale, Nicola Silvestris, Letizia Porcelli, Oronzo Brunetti, Marzia Del Re, Vito Longo, Patrizia Nardulli, Michele Signorile, Angela Calabrese, Evaristo Maiello, Vito Lorusso, and Jian-Ming Xu, “Total and not bevacizumab-bound vascular endothelial growth factor as potential predictive factors to bevacizumab-based chemotherapy in colorectal cancer,” World Journal of Gastroenterology, vol. 22, no. 27, pp. 6287–6295, 2016. View at Publisher · View at Google Scholar
  • Kazunori Fugo, Yasufumi Motoyoshi, Takao Sugiyama, Takashi Kishimoto, Naoki Ishige, Midori Noritake, Minoru Tomizawa, Shigenori Yamamoto, Mizuki Togashi, Fuminobu Shinozaki, Rumiko Hasegawa, Yoshinori Shirai, Yukie Matsuoka, Hiroaki Kainuma, and Yasuji Iwasaki, “Unenhanced areas revealed by contrast-enhanced abdominal ultrasonography with Sonazoid™ potentially correspond to colorectal cancer,” Experimental and Therapeutic Medicine, vol. 12, no. 6, pp. 4012–4016, 2016. View at Publisher · View at Google Scholar
  • Nikolett M. Biel, and Dietmar W. Siemann, “Targeting the Angiopoietin-2/Tie-2 axis in conjunction with VEGF signal interference,” Cancer Letters, vol. 380, no. 2, pp. 525–533, 2016. View at Publisher · View at Google Scholar
  • Olivera Mitrović Ajtić, Slobodan Todorović, Miloš Diklić, Tijana Subotički, Bojana Beleslin-Čokić, Gordana Jovčić, and Vladan Čokić, “Proliferation and differentiation markers of colorectal adenocarcinomaand their correlation with clinicopathological factors,” Turkish Journal Of Medical Sciences, vol. 46, pp. 1168–1176, 2016. View at Publisher · View at Google Scholar
  • Amara G. Nandikolla, and Lakshmi Rajdev, “Targeting angiogenesis in gastrointestinal tumors: Current challenges,” Translational Gastroenterology and Hepatology, vol. 2016, 2016. View at Publisher · View at Google Scholar
  • Hongbo Wang, and Anna M. Mahecha, “The influence of vascular endothelial growth factor-A and matrix metalloproteinase-2 and -9 in angiogenesis, metastasis, and prognosis of endometrial cancer,” OncoTargets and Therapy, vol. 10, pp. 4617–4624, 2017. View at Publisher · View at Google Scholar
  • Zhiwei Zhao, Shichao Wang, Yingbo Lin, Yali Miao, Ye Zeng, Yongmei Nie, Peng Guo, Guangyao Jiang, and Jiang Wu, “Epithelial-mesenchymal transition in cancer: Role of the IL-8/IL-8R axis,” Oncology Letters, vol. 13, no. 6, pp. 4577–4584, 2017. View at Publisher · View at Google Scholar
  • Cesare Ruffolo, Angelo P Dei Tos, Carlo Castoro, Nicolò Bassi, Marco Scarpa, Luisa Toffolatti, Fabio Canal, Andromachi Kotsafti, Giulia Pagura, Anna Pozza, Marta Campo Dell’Orto, Francesco Ferrara, and Marco Massani, “Colorectal polypoid lesions and expression of vascular endothelial growth factor in a consecutive series of endoscopic and surgical patients,” Tumor Biology, vol. 39, no. 3, 2017. View at Publisher · View at Google Scholar
  • Carlos Bais, Michael J. Birrer, Barbara Mueller, Mark F. Brady, Robert A. Burger, Wei Wei, Robert S. Mannel, Koen M. Marien, Mark M. Kockx, and Amreen Husain, “Tumor Microvessel Density as a Potential Predictive Marker for Bevacizumab Benefit: GOG-0218 Biomarker Analyses,” Journal of the National Cancer Institute, vol. 109, no. 11, 2017. View at Publisher · View at Google Scholar
  • Salem Y. Mohamed, Hanan Lotfy Mohammed, Hanaa M. Ibrahim, Elshaimaa M. Mohamed, and Mona Salah, “Role of VEGF, CD105, and CD31 in the Prognosis of Colorectal Cancer Cases,” Journal of Gastrointestinal Cancer, 2017. View at Publisher · View at Google Scholar
  • Jun Xue, Ming Qu, Fei Guo, Guang-Yuan Sun, Peng-Cheng Zhang, Lei Han, Xue-Liang Wu, Xian-Tao Huang, and Li-Ming Pan, “Correlation of RUNX3 expression with microvessel density in colorectal adenocarcinoma tissues and clinical significance,” Asian Pacific Journal of Tropical Medicine, vol. 10, no. 1, pp. 98–101, 2017. View at Publisher · View at Google Scholar
  • Marcin Bobiński, Wiesława Bednarek, Karolina Okła, Iwona Wertel, Jan Kotarski, Grzegorz Polak, and Małgorzata Sobstyl, “Does the patients age at cancer diagnosis affect microvessels density in uterine sarcoma tissues?,” Ginekologia Polska, vol. 88, no. 3, pp. 138–140, 2017. View at Publisher · View at Google Scholar
  • Adriano Angelucci, Simona Delle Monache, Alessio Cortellini, Monica Di Padova, and Corrado Ficorella, ““Vessels in the Storm”: Searching for Prognostic and Predictive Angiogenic Factors in Colorectal Cancer,” International Journal of Molecular Sciences, vol. 19, no. 2, pp. 299, 2018. View at Publisher · View at Google Scholar
  • Hugh Mulcahy, David Fennelly, Jacintha O'Sullivan, Maria E. Morrissey, Aoife Maguire, Kieran Sheahan, Shane ó'Meachair, Sinead A. Noonan, Diarmuid O'Donoghue, Blathnaid Nolan, Petra Martin, Monika Biniecka, Miriam Tosetto, and John Hyland, “Tumour vasculature immaturity, oxidative damage and systemic inflammation stratify survival of colorectal cancer patients on bevacizumab treatment,” Oncotarget, vol. 9, no. 12, pp. 10536–10548, 2018. View at Publisher · View at Google Scholar
  • Marcin Bobiński, Karolina Okła, Grzegorz Polak, Wiesława Bednarek, Jan Kotarski, Justyna Szumiło, and Małgorzata Sobstyl, “Neuropilin 1 in uterine leiomyosarcoma. Clinical and pathological analysis,” Ginekologia Polska, vol. 89, no. 1, pp. 7–12, 2018. View at Publisher · View at Google Scholar