Table of Contents Author Guidelines Submit a Manuscript
Table of Contents Alerts

To receive news and publication updates for The Scientific World Journal, enter your email address in the box below.

The Scientific World Journal
Volume 2014, Article ID 103462, 15 pages
http://dx.doi.org/10.1155/2014/103462
Research Article

Direct Synthesis and Morphological Characterization of Gold-Dendrimer Nanocomposites Prepared Using PAMAM Succinamic Acid Dendrimers: Preliminary Study of the Calcification Potential

E. Vasile,1 A. Serafim,2 D. Petre,2 D. Giol,3 P. Dubruel,3 H. Iovu,2 and I. C. Stancu2

1METAV Research and Development, 31 C.A. Rosetti, Sector 2, 020015 Bucharest, Romania
2Advanced Polymer Materials Group, University Politehnica of Bucharest, 149 Calea Victoriei, Sector 1, 010072 Bucharest, Romania
3Polymer Chemistry and Biomaterials Group, Ghent University, Krijgslaan 281 (S4), 9000 Ghent, Belgium

Received 30 August 2013; Accepted 12 November 2013; Published 28 January 2014

Academic Editors: L. Visai and C.-H. Yao

Copyright © 2014 E. Vasile et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. Tang, J. Tang, B. Su, and G. Chen, “Gold nanoparticles-decorated amine-terminated poly(amidoamine) dendrimer for sensitive electrochemical immunoassay of brevetoxins in food samples,” Biosensors and Bioelectronics, vol. 26, no. 5, pp. 2090–2096, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. E. Vasile, A. Serafim, D.-M. Dragusin, C. Petrea, H. Iovu, and I.-C. Stancu, “Apatite formation on active nanostructured coating based on functionalized gold nanoparticles,” Journal of Nanoparticle Research, vol. 14, no. 6, article 918, 2012. View at Google Scholar
  3. C. Ajaero, M. Y. M. Abdelrahimb, J. M. Palacios-Santander et al., “Comparative study of the electrocatalytic activity of different types of gold nanoparticles using Sonogel-Carbon material as supporting electrode,” Sensors and Actuators B, vol. 171-172, pp. 1244–1256, 2012. View at Google Scholar
  4. P. Ghosh, G. Han, M. De, C. K. Kim, and V. M. Rotello, “Gold nanoparticles in delivery applications,” Advanced Drug Delivery Reviews, vol. 60, no. 11, pp. 1307–1315, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Granmayeh Rad, H. Abbasi, and M. H. Afzali, “Gold nanoparticles: synthesising, characterizing and reviewing novel application in recent years,” Physics Procedia, vol. 22, pp. 203–208, 2011. View at Google Scholar
  6. P. Krystek, “A review on approaches to bio distribution studies about gold and silver engineered nanoparticles by inductively coupled plasma mass spectrometry,” Microchemical Journal, vol. 105, pp. 39–43, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. C. Lasagna-Reeves, D. Gonzalez-Romero, M. A. Barria et al., “Bioaccumulation and toxicity of gold nanoparticles after repeated administration in mice,” Biochemical and Biophysical Research Communications, vol. 393, no. 4, pp. 649–655, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. D. Pissuwan, T. Niidome, and M. B. Cortie, “The forthcoming applications of gold nanoparticles in drug and gene delivery systems,” Journal of Controlled Release, vol. 149, no. 1, pp. 65–71, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. V. Venkatpurwar, A. Shiras, and V. Pokharkar, “Porphyran capped gold nanoparticles as a novel carrier for delivery of anticancer drug: in vitro cytotoxicity study,” International Journal of Pharmaceutics, vol. 409, no. 1-2, pp. 314–320, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. P. Li, A. Lappas, R. Lavieville, Y. Zhang, and R. Krahne, “CdSe-Au nanorod networks welded by gold domains: a promising structure for nano-optoelectronic components,” Journal of Nanoparticle Research, vol. 14, no. 7, pp. 1–5, 2012. View at Google Scholar
  11. D. Astruc, “Transition-metal nanoparticles in catalysis: from historical background to the state-of-the art,” in Nanoparticles and Catalysis, pp. 1–48, Wiley-VCH GmbH & Co. KGaA, 2008. View at Google Scholar
  12. L. Balogh, R. Valluzzi, K. S. Laverdure, S. P. Gido, G. L. Hagnauer, and D. A. Tomalia, “Formation of silver and gold dendrimer nanocomposites,” Journal of Nanoparticle Research, vol. 1, no. 3, pp. 353–368, 1999. View at Google Scholar · View at Scopus
  13. T. Endo, T. Yoshimura, and K. Esumi, “Synthesis and catalytic activity of gold-silver binary nanoparticles stabilized by PAMAM dendrimer,” Journal of Colloid and Interface Science, vol. 286, no. 2, pp. 602–609, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Kavitha, M. R. Parida, E. Prasad, C. Vijayan, and P. C. Deshmukh, “Generation of Ag nanoparticles by PAMAM dendrimers and their size dependence on the aggregation behavior of dendrimersa,” Macromolecular Chemistry and Physics, vol. 210, no. 16, pp. 1310–1318, 2009. View at Publisher · View at Google Scholar · View at Scopus
  15. O. V. Lebedeva, B.-S. Kim, F. Gröhn, and O. I. Vinogradova, “Dendrimer-encapsulated gold nanoparticles as building blocks for multilayer microshells,” Polymer, vol. 48, no. 17, pp. 5024–5029, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. H. Liu, K. Sun, J. Zhao et al., “Dendrimer-mediated synthesis and shape evolution of gold-silver alloy nanoparticles,” Colloids and Surfaces A, vol. 405, pp. 22–29, 2012. View at Google Scholar
  17. C. Peng, L. Zheng, Q. Chen et al., “PEGylated dendrimer-entrapped gold nanoparticles for in vivo blood pool and tumor imaging by computed tomography,” Biomaterials, vol. 33, no. 4, pp. 1107–1119, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. X. Shi, T. R. Ganser, K. Sun, L. P. Balogh, and J. R. Baker Jr., “Characterization of crystalline dendrimer-stabilized gold nanoparticles,” Nanotechnology, vol. 17, no. 4, pp. 1072–1078, 2006. View at Publisher · View at Google Scholar · View at Scopus
  19. P.-G. Su and W.-H. Tzou, “Low-humidity sensing properties of PAMAM dendrimer and PAMAM-Au nanoparticles measured by a quartz-crystal microbalance,” Sensors and Actuators A, vol. 179, pp. 44–49, 2012. View at Publisher · View at Google Scholar · View at Scopus
  20. H. Wu, Z. Liu, X. Wang, B. Zhao, J. Zhang, and C. Li, “Preparation of hollow capsule-stabilized gold nanoparticles through the encapsulation of the dendrimer,” Journal of Colloid and Interface Science, vol. 302, no. 1, pp. 142–148, 2006. View at Publisher · View at Google Scholar · View at Scopus
  21. A. Castonguay and A. K. Kakkar, “Dendrimer templated construction of silver nanoparticles,” Advances in Colloid and Interface Science, vol. 160, no. 1-2, pp. 76–87, 2010. View at Publisher · View at Google Scholar · View at Scopus
  22. F. Divsar, A. Nomani, M. Chaloosi, and I. Haririan, “Synthesis and characterization of gold nanocomposites with modified and intact polyamidoamine dendrimers,” Microchimica Acta, vol. 165, no. 3-4, pp. 421–426, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. T. Pietsch, D. Appelhans, N. Gindy, B. Voit, and A. Fahmi, “Oligosaccharide-modified dendrimers for templating gold nanoparticles: tailoring the particle size as a function of dendrimer generation and -molecular structure,” Colloids and Surfaces A, vol. 341, no. 1–3, pp. 93–102, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. H. Liu, M. Shen, J. Zhao et al., “Tunable synthesis and acetylation of dendrimer-entrapped or dendrimer-stabilized gold-silver alloy nanoparticles,” Colloids and Surfaces B, vol. 94, pp. 58–67, 2012. View at Publisher · View at Google Scholar · View at Scopus
  25. Y. Luo, “Size-controlled preparation of dendrimer-protected gold nanoparticles: a sunlight irradiation-based strategy,” Materials Letters, vol. 62, no. 21-22, pp. 3770–3772, 2008. View at Publisher · View at Google Scholar · View at Scopus
  26. X. Sun and Y. Luo, “Size-controlled synthesis of dendrimer-protected gold nanoparticles by microwave radiation,” Materials Letters, vol. 59, no. 29-30, pp. 4048–4050, 2005. View at Publisher · View at Google Scholar · View at Scopus
  27. B. Pan, F. Gao, L. Ao, H. Tian, R. He, and D. Cui, “Controlled self-assembly of thiol-terminated poly(amidoamine) dendrimer and gold nanoparticles,” Colloids and Surfaces A, vol. 259, no. 1–3, pp. 89–94, 2005. View at Publisher · View at Google Scholar · View at Scopus
  28. T. Endo, T. Yoshimura, and K. Esumi, “Voltammetric study of sodium hypochlorite using dendrimer-stabilized gold nanoparticles,” Journal of Colloid and Interface Science, vol. 269, no. 2, pp. 364–369, 2004. View at Publisher · View at Google Scholar · View at Scopus
  29. X. Shi, K. Sun, and J. R. Baker Jr., “Spontaneous formation of functionalized dendrimer-stabilized gold nanoparticles,” Journal of Physical Chemistry C, vol. 112, no. 22, pp. 8251–8258, 2008. View at Publisher · View at Google Scholar · View at Scopus
  30. X. Shi, S. H. Wang, M. E. van Antwerp, X. Chen, and J. R. Baker Jr., “Targeting and detecting cancer cells using spontaneously formed multifunctional dendrimer-stabilized gold nanoparticles,” Analyst, vol. 134, no. 7, pp. 1373–1379, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. M. Shen, K. Sun, and X. Shi, “Hydroxylated dendrimer-stabilized gold and silver nanoparticles: spontaneous formation, characterization, and surface properties,” Current Nanoscience, vol. 6, no. 3, pp. 307–314, 2010. View at Publisher · View at Google Scholar · View at Scopus
  32. X. Sun, S. Dong, and E. Wang, “One-step preparation and characterization of poly(propyleneimine) dendrimer-protected silver nanoclusters,” Macromolecules, vol. 37, no. 19, pp. 7105–7108, 2004. View at Publisher · View at Google Scholar · View at Scopus
  33. I.-C. Stancu, R. Filmon, C. Cincu et al., “Synthesis of methacryloyloxyethyl phosphate copolymers and in vitro calcification capacity,” Biomaterials, vol. 25, no. 2, pp. 205–213, 2004. View at Publisher · View at Google Scholar · View at Scopus
  34. T. Kawai, C. Ohtsuki, M. Kamitakahara et al., “Coating of an apatite layer on polyamide films containing sulfonic groups by a biomimetic process,” Biomaterials, vol. 25, no. 19, pp. 4529–4534, 2004. View at Publisher · View at Google Scholar · View at Scopus
  35. R. Filmon, F. Grizon, M. F. Baslé, and D. Chappard, “Effects of negatively charged groups (carboxymethyl) on the calcification of poly(2-hydroxyethyl methacrylate),” Biomaterials, vol. 23, no. 14, pp. 3053–3059, 2002. View at Publisher · View at Google Scholar · View at Scopus
  36. M. Kawashita, M. Nakao, M. Minoda et al., “Apatite-forming ability of carboxyl group-containing polymer gels in a simulated body fluid,” Biomaterials, vol. 24, no. 14, pp. 2477–2484, 2003. View at Publisher · View at Google Scholar · View at Scopus
  37. M. Tanahashi and T. Matsuda, “Surface functional group dependence on apatite formation on self-assembled monolayers in a simulated body fluid,” Journal of Biomedical Materials Research, vol. 34, no. 3, pp. 305–315, 1997. View at Google Scholar
  38. J. L. Brown, L. S. Nair, J. Bender, H. R. Allcock, and C. T. Laurencin, “The formation of an apatite coating on carboxylated polyphosphazenes via a biomimetic process,” Materials Letters, vol. 61, no. 17, pp. 3692–3695, 2007. View at Publisher · View at Google Scholar · View at Scopus
  39. J. J. J. M. Donners, R. J. M. Nolte, and N. A. J. M. Sommerdijk, “Dendrimer-based hydroxyapatite composites with remarkable materials properties,” Advanced Materials, vol. 15, no. 4, pp. 313–316, 2003. View at Publisher · View at Google Scholar · View at Scopus
  40. A. Lungu, E. Rusen, L. M. Butac, and I.-C. Stancu, “Epoxy-mediated immobilization of PAMAM dendrimers on methacrylic hydrogels,” Digest Journal of Nanomaterials and Biostructures, vol. 4, no. 1, pp. 97–107, 2009. View at Google Scholar · View at Scopus
  41. A. Lungu, I.-C. Stancu, E. Rusen, B. Mǎrculescu, and H. Iovu, “Studies concerning the chemical immobilization of dendrimers on macroporous polymer matrix,” Journal of Optoelectronics and Advanced Materials, vol. 9, no. 11, pp. 3454–3458, 2007. View at Google Scholar · View at Scopus
  42. I.-C. Stancu, “SPR Imaging label-free control of biomineral nucleation!?” in Intelligent and Biosensors, V. S. Somerset, Ed., InTech, 2010. View at Google Scholar
  43. P. Elter, F. Sickel, and A. Ewald, “Nanoscaled periodic surface structures of medical stainless steel and their effect on osteoblast cells,” Acta Biomaterialia, vol. 5, no. 5, pp. 1468–1473, 2009. View at Publisher · View at Google Scholar · View at Scopus
  44. C. J. Frandsen, K. S. Brammer, K. Noh et al., “Zirconium oxide nanotube surface prompts increased osteoblast functionality and mineralization,” Materials Science and Engineering C, vol. 31, no. 8, pp. 1716–1722, 2011. View at Publisher · View at Google Scholar · View at Scopus
  45. M. Voisin, M. Ball, C. O'Connell, and R. Sherlock, “Osteoblasts response to microstructured and nanostructured polyimide film, processed by the use of silica bead microlenses,” Nanomedicine, vol. 6, no. 1, pp. e35–e43, 2010. View at Publisher · View at Google Scholar · View at Scopus
  46. G. Wang, X. Liu, H. Zreiqat, and C. Ding, “Enhanced effects of nano-scale topography on the bioactivity and osteoblast behaviors of micron rough ZrO2 coatings,” Colloids and Surfaces B, vol. 86, no. 2, pp. 267–274, 2011. View at Publisher · View at Google Scholar · View at Scopus
  47. G. Wang, F. Meng, C. Ding, P. K. Chu, and X. Liu, “Microstructure, bioactivity and osteoblast behavior of monoclinic zirconia coating with nanostructured surface,” Acta Biomaterialia, vol. 6, no. 3, pp. 990–1000, 2010. View at Publisher · View at Google Scholar · View at Scopus
  48. C.-H. Kiang, “Phase transition of DNA-linked gold nanoparticles,” Physica A, vol. 321, no. 1-2, pp. 164–169, 2003. View at Publisher · View at Google Scholar · View at Scopus