Preparation of Tween 80-Zn/Al-Levodopa-Layered Double Hydroxides Nanocomposite for Drug Delivery System

Table 1

Correlation coefficients (𝑅²) and rate constants (𝑘) obtained by fitting the dopa release data for the coated nanocomposite in buffer solutions at pH 4.8 and 7.4.

pH	Saturation release (%)	𝑅^2			Rate constant (𝑘)
		Pseudo-first-order	Pseudo-second-order	Parabolic diffusion model
7.4	78%	0.8983	0.9718	0.9828	(9.8 × 10^−3)^a
4.8	75%	0.9224	0.9803	0.9689	(8.2 × 10^−6)^b

Notes: ^aestimated using parabolic diffusion model; ^bestimated using pseudo-second-order kinetics.