Mitigative Effect of Erythromycin on PMMA Challenged Preosteoblastic MC3T3-E1 Cells
Figure 4
Effects of EM on gene expression of NF-κB, Runx2, osterix, and osteocalcinin MC3T3 cells 7 days in culture. An increase of NF-κB (2.8-fold) was observed in MC3T3 cells challenged with PMMA particles, compared to PBS control. This increase was significantly reduced by EM treatment, as determined by ANOVA analysis. Values are means ± SEM of genes measured for triplicate and the experiments repeated three times. cells + PMMA versus control (cell alone); for PMMA with EM treatment versus PMMA without EM treatment.
