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The Scientific World Journal
Volume 2014, Article ID 120891, 6 pages
Research Article

Consent to Specimen Storage and Continuing Studies by Race and Ethnicity: A Large Dataset Analysis Using the 2011-2012 National Health and Nutrition Examination Survey

1Department of Medicine, Division of Pulmonary, Allergy, & Critical Care Medicine, Columbia University Medical Center, 622 West 168 Street, New York, NY 10032, USA
2Center for Health Policy, Columbia University School of Nursing, 630 West 168th Street, New York, NY 10032, USA
3Columbia University School of Nursing, 630 West 168th Street, New York, NY 10032, USA

Received 1 May 2014; Revised 29 September 2014; Accepted 29 September 2014; Published 18 November 2014

Academic Editor: Vinicius C. Antao

Copyright © 2014 Andre Gabriel et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To determine if significant differences exist in consent rates for biospecimen storage and continuing studies between non-Hispanic Whites and minority ethnic groups in the National Health and Nutrition Examination Survey (NHANES). Methods. Using logistic regression, we analyzed 2011-2012 NHANES data to determine whether race/ethnicity, age, gender, and education level influence consent to specimen storage or future testing. Results. Compared to non-Hispanic Whites, some minorities were less willing to donate a specimen for storage and continuing studies, including other Hispanics (non-Mexican) (OR 0.236, 95% CI: 0.079, 0.706), non-Hispanic Asians (OR 0.212, 95% CI: 0.074, 0.602), and other/multiracial ethnic groups (OR 0.189, 95% CI: 0.037, 0.957). Within race and ethnic groups, those aged 20–39 years (OR 2.215, 95% CI: 1.006–4.879) and 40–59 years (OR 9.375, 95% CI: 2.163–40.637) are more willing than those over 60 years to provide consent. Conclusion. Lower consent rates by other Hispanics, non-Hispanic Asians, and other/multiracial individuals in this study represent the first published comparison of consent rates among these groups to our knowledge. To best meet the health care needs of this segment of the population and to aid in designing future genetic studies, reassessment of ethnic minority groups concerning these issues is important.