Effect of Electroacupuncture on Rats with Chronic Constriction Injury-Induced Neuropathic Pain

Table 3

Effect of electroacupuncture (EA) on von Frey test in SD rats with chronic constriction injury (CCI)-induced neuropathic pain (counts).

	Normal	Control	Sham	2EA	15EA
D5	39.76 ± 1.58	11.82 ± 1.76*	11.33 ± 1.08*	11.82 ± 3.48*	11.23 ± 0.91*
D6	36.50 ± 6.54	10.93 ± 4.12*	12.70 ± 2.00*	20.07±1.74^∗#¶	18.48±2.42^∗#¶
D7	40.51 ± 2.10	11.21 ± 3.84*	12.97 ± 2.65*	18.59±2.16^∗#¶	18.13±1.58^∗#¶
D8	40.54 ± 3.01	9.91 ± 2.48*	10.97 ± 2.03*	18.53±2.29^∗#¶	17.94±1.90^∗#¶
D11	40.23 ± 4.99	9.38 ± 3.36*	9.26 ± 1.95*	18.87±2.33^∗#¶	17.94±1.93^∗#¶
D12	41.59 ± 3.01	8.86 ± 2.14*	10.03 ± 2.15*	20.37±3.29^∗#¶	19.72±1.76^∗#¶
D13	41.26 ± 5.13	7.99 ± 2.17*	8.26 ± 1.70*	17.81±2.79^∗#¶	20.14±1.65^∗#¶

Data represent mean ± standard deviation. 𝑁=9; normal: normal group, no CCI, no EA; control: control group, CCI without EA; Sham: sham group, CCI with sham EA; 2EA: 2EA group, CCI with 2 Hz EA on ipsilateral Zusanli and Shangjuxu acupoints; 15EA: 15EA group, CCI with 15 Hz EA on ipsilateral Zusanli and Shangjuxu acupoints; D5: 5th day following ligation; D6: 6th day following ligation; D7: 7th day after operation; D8: 8th day following ligation; D11: 11th day following ligation; D12: 12th day following ligation; D13: 13th day following ligation; *P < .001 compared with normal; ^#P < .001 compared with control; ¶P < 0.001 compared with sham.