Prediction of Early Response to Chemotherapy in Lung Cancer by Using Diffusion-Weighted MR Imaging

Table 1

Patient and tumor characteristics between the PR and SD groups.

Characteristics	PR (𝑛=8)	SD (𝑛=17)	𝑃
Age (years)	66 (56–69)	59 (56–66)	0.587
Female/male	1/7	7/10	0.205
Smoker	4	9	0.891
Lesion location			0.389
Right lobe	3	11
Left lobe	5	6
Histological subtype			0.089
Squamous cell carcinomas	7	7
Adenocarcinomas	1	8
Adenosquamous carcinomas	0	2
Stage			0.456
III A	3	8
III B	5	7
IV	0	2
ADC at baseline (10^−3 mm^2/s)	1.26±0.17	1.20±0.20	0.517
Change of longest diameter (cm)	1.76±0.92	0.61±0.88	0.007
Change of shortest diameter (cm)	1.11±0.11	0.37±0.66	0.045
Change of ADC value (10^−3 mm^2/s)	0.90±0.25	0.37±0.42	0.004

ADC: apparent diffusion coefficient; PR: partial response; SD: stable disease.