Surgical Treatment of Perianal Fistulizing Crohn’s Disease: From Lay-Open to Cell-Based Therapy—An Overview

Figure 1

Forest plot of the failure (event) of patients undergoing plug procedure with (CD) or without (no CD) diagnosis of Crohn’s disease. Only papers in which CD could clearly be identified and only patients with complex fistulae were included. No differences were observed between Crohn’s disease patients and controls (OR 0.86, 95%CI 0.28–2.62, ) (Mantel-Haenszel fixed effect). Low heterogeneity is observed: %.