Review Article
Today Prospects for Tissue Engineering Therapeutic Approach in Dentistry
Table 1
In vivo studies dealing with dental stem cells applications in tissue engineering procedures.
| Type of cell | Origin | Year | Reference | Scaffold | GFs | Animal model | Type of differentiation |
| DFSC | Bovine | 2002 | Handa et al. [52] | HA ceramic powder | | Mice | Cementoblastic | Human | 2011 | Honda et al. [53] | Pellet culture system | | Rat | Osteoblastic | Pig | 2008 | Tsuchiya et al. [54] | β-TCP | | Mice | Osteoblastic | Human | 2005 | Morsczeck et al. [10] | HA ceramic powder | | Mice | Osteoblastic | Human | 2010 | Yagyuu et al. [55] | Porous ceramic discs | | Rat | Cementoblastic |
| DPSC | Dog, pig | 2004 | Iohara et al. [41] | Pellet culture system | BMP-2 | Dog | Odontoblastic | Human | 2011 | Alsanea et al. [37] | Collagen/dentin wafer | DMP-1 | Mice | Odontoblastic | Pig | 2008 | Prescott et al. [36] | Collagen/tooth slice | DMP-1 | Mice | Odontoblastic | Pig | 2012 | Kodonas et al. [44] | Collagen/PLGA | | Pig | Odontoblastic | Human | 2011 | Chan et al. [50] | Peptide hydrogel | | Mice | Osteoblastic | Human | 2010 | Demarco et al. [35] | PLLA/tooth slice and porogens | | Mice | Odontoblastic | Human | 2000 | Gronthos et al. [7] | HA/TCP ceramic powder | | Mice | Odontoblastic | Human | 2010 | Kraft et al. [51] | HA/TCP granules | | Mice | Osteoblastic and odontoblastic | Dog | 2013 | Wang et al. [45] | HA ceramic powder | | Dog | Odontoblastic | Dog | 2013 | Khorsand et al. [56] | Bovine bone granules | | Dog | Osteoblastic, cementoblastic, and fibroblastic | Rabbit | 2008 | El-Backly et al. [43] | DL-lactide-CO-glycolide | | Rabbit | Odontoblastic | Pig | 2012 | Zheng et al. [42] | β-TCP | | Swine | Odontoblastic | Rat | 2013 | Tsujigiwa et al. [46] | β-TCP particles | | Mice | Odontoblastic | Human | 2014 | Syed-Picard et al. [40] | 3D scaffoldless DPSCs/root canal | | Mice | Odontoblastic | Human | 2005 | Laino et al. [48] | Fibrous bone obtained in vitro | | Mice | Osteoblastic | Human | 2007 |
d’Aquino et al. [49] | Bone chips obtained in vitro | | Mice | Osteoblastic |
| PDLSC | Dog | 2012 | Suaid et al. [57] | Collagen sponge | | Dog | Cementoblastic and fibroblastic | Dog | 2012 | Wang et al. [58] | HA ceramic particles | | Mice | Fibroblastic | Human | 2004 | Seo et al. [8] | HA/TCP ceramic particles | | Rat | Cementoblastic and fibroblastic | Dog | 2009 | Kim et al. [59] | HA/TCP granules | | Dog | Osteoblastic | Human | 2011 | Park et al. [60] | Macroporous biphasic calcium phosphate | | Mice | Cementoblastic | Human | 2013 | Ji et al. [61] | Human dentine bocks | | Mice | Cementoblastic and fibroblastic | Dog | 2014 | Yu et al. [62] | Bovine bone granules | | Dog | Osteoblastic | Rat | 2014 | Han et al. [63] | Adsorbable gelatin sponge | | Rat | Osteoblastic, cementoblastic, and fibroblastic | Human | 2006 | Sonoyama et al. [25] | HA/TCP blocks | | Swine | Cementoblastic and fibroblastic |
| SHED | Human | 2012 | Wang et al. [64] | Ceramic bovine bone (CBB); fibrin gel | | Mice | Osteoblastic | Human | 2010 | Sakai et al. [65] | PLLA/tooth slice | | Mice | Odontoblastic | Human | 2013 | Rosa et al. [66] | Peptide hydrogel or rH collagen in root canal | | Mice | Odontoblastic | Human | 2013 | Alkaisi et al. [67] | Cell pellets | | Rat | Osteoblastic | Human | 2014 | Kim et al. [68] | Macroporous biphasic calcium phosphate | FGF-2 | Mice | Odontoblastic | Human | 2010 | Casagrande et al. [69] | PLLA/tooth slice | | Mice | Odontoblastic | Human | 2008 | Cordeiro et al. [70] | PLLA/tooth slice | | Mice | Odontoblastic | Human | 2003 | Miura et al. [9] | HA/TCP ceramic powder | | Mice | Osteoblastic and odontoblastic | Human | 2008 | Seo et al. [71] | HA/TCP particles | | Mice | Osteoblastic |
| SCAP | Human | 2006 | Sonoyama et al. [25] | HA/TCP blocks | | Swine | Odontoblastic | Human | 2012 | Abe et al. [72] | HA/TCP particles | | Mice | Osteoblastic | Human | 2010 | Yagyuu et al. [55] | Porous ceramic discs | | Rat | Odontoblastic |
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