AcT-2: A Novel Myotropic and Antimicrobial Type 2 Tryptophyllin from the Skin Secretion of the Central American Red-Eyed Leaf Frog, Agalychnis callidryas
Minimal inhibitory concentration (MIC) curves obtained following incubation of synthetic AcT-2 with S. aureus (a), E. coli (b), and C. albicans (c). The MIC value for each microorganism is indicated in respective panels by asterisks. (d) The hemolytic activity of synthetic AcT-2. The arrow shows the highest concentration of peptide (512 mg/L) which was the only concentration at which hemolysis was observed (8.5%).
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