Table of Contents Author Guidelines Submit a Manuscript
The Scientific World Journal
Volume 2014, Article ID 165351, 8 pages
Research Article

Antimicrobial Activity of Thin Solid Films of Silver Doped Hydroxyapatite Prepared by Sol-Gel Method

1National Institute of Materials Physics, P.O. Box MG 07, Magurele, Romania
2Horiba Jobin Yvon S.A., 16-18 rue du Canal, 91165 Longjumeau Cedex, France
3Universite Bordeaux, EA 4592 Géoressources & Environnement, ENSEGID, 1 allée F. Daguin, 33607 Pessac Cedex, France

Received 21 August 2013; Accepted 20 October 2013; Published 12 January 2014

Academic Editors: M. Chipara and K. Liu

Copyright © 2014 Simona Liliana Iconaru et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


In this work, the preparation and characterization of silver doped hydroxyapatite thin films were reported and their antimicrobial activity was characterized. Silver doped hydroxyapatite (Ag:HAp) thin films coatings substrate was prepared on commercially pure Si disks by sol-gel method. The silver doped hydroxyapatite thin films were characterized by various techniques such as Scanning electron microscopy (SEM) with energy Dispersive X-ray attachment (X-EDS), Fourier transform infrared spectroscopy (FT-IR), and glow discharge optical emission spectroscopy (GDOES). These techniques have permitted the structural and chemical characterisation of the silver doped hydroxyapatite thin films. The antimicrobial effect of the Ag:HAp thin films on Escherichia coli and Staphylococcus aureus bacteria was then investigated. This is the first study on the antimicrobial effect of Ag:HAp thin films obtained by sol-gel method. The results of this study have shown that the Ag:HAp thin films with are effective against E. coli and S. aureus after 24 h.