Antiproliferative Effects of Methanolic Extracts of Cryptocarya concinna Hance Roots on Oral Cancer Ca9-22 and CAL 27 Cell Lines Involving Apoptosis, ROS Induction, and Mitochondrial Depolarization

Figure 3

Apoptosis of two oral cancer cells was induced by MECCrt. Oral cancer Ca9-22 and CAL 27 cell lines were treated with 0–25 μg/mL of MECCrt for 24 h. ((a) and (b)) Representative results of annexin V/PI double staining of flow cytometry for MECCrt-treated oral cancer Ca9-22 and CAL 27 cell lines and vehicle controls at 24 h, respectively. ((c) and (d)) Quantification analysis of apoptosis for MECCrt-treated oral cancer Ca9-22 and CAL 27 cell lines in (a) and (b), respectively. Data, means ± SDs (). against vehicle.

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