Research Article

Antiproliferative Effects of Methanolic Extracts of Cryptocarya concinna Hance Roots on Oral Cancer Ca9-22 and CAL 27 Cell Lines Involving Apoptosis, ROS Induction, and Mitochondrial Depolarization

Figure 4

Reactive oxygen species (ROS) generation of two oral cancer cell lines was induced by MECCrt. Oral cancer Ca9-22 and CAL 27 cell lines were treated with different concentrations (0–25 μg/mL) of MECCrt for 6 and 12 h. ((a), (b)) Representative ROS profiles of flow cytometry for MECCrt-treated oral cancer Ca9-22 and CAL 27 cell lines. ((c) and (d)) Statistics analysis of relative ROS intensity in (a) and (b), respectively. Data, means ± SDs (). against vehicle.
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