Research Article
Antiproliferative Effects of Methanolic Extracts of Cryptocarya concinna Hance Roots on Oral Cancer Ca9-22 and CAL 27 Cell Lines Involving Apoptosis, ROS Induction, and Mitochondrial Depolarization
Figure 4
Reactive oxygen species (ROS) generation of two oral cancer cell lines was induced by MECCrt. Oral cancer Ca9-22 and CAL 27 cell lines were treated with different concentrations (0–25 μg/mL) of MECCrt for 6 and 12 h. ((a), (b)) Representative ROS profiles of flow cytometry for MECCrt-treated oral cancer Ca9-22 and CAL 27 cell lines. ((c) and (d)) Statistics analysis of relative ROS intensity in (a) and (b), respectively. Data, means ± SDs (). against vehicle.
(a) |
(b) |
(c) |
(d) |