Antiproliferative Effects of Methanolic Extracts of Cryptocarya concinna Hance Roots on Oral Cancer Ca9-22 and CAL 27 Cell Lines Involving Apoptosis, ROS Induction, and Mitochondrial Depolarization

Figure 5

Depolarization of mitochondrial membrane potential (MMP) of Ca9-22 and CAL 27 oral cancer cell lines was induced by MECCrt. Oral cancer Ca9-22 and CAL 27 cell lines were treated with different concentrations (0–25 μg/mL) of MECCrt for 24 h. ((a), (b)) Representative MMP profiles of flow cytometry for MECCrt-treated oral cancer Ca9-22 and CAL 27 cells. ((c) and (d)) Quantification analysis of relative MMP intensity in (a) and (b), respectively. Data, means ± SDs (). and against vehicle.

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