Research Article
Evaluation of Halogenated Coumarins for Antimosquito Properties
Table 1
Physicochemical characteristics of 3-mono/dibromoacetyl-6-halogenated coumarin analogues CMRN 1–CMRN 7.
| | Code | M. F (M. Wt.) | Yield (%)a,b | m.p. (°C) reported | m.p. (°C) found | Mass () | |
| | CMRN 1 | C11H7BrO3 (265) | 96 | 120–122 | 121 | 266 () | 1.4023 | | CMRN 2 | C11H5Br3O3 (421) | 95 | 146–148 | 147 | 422 () | 3.4753 | | CMRN 3 | C11H7BrO3 (265) | 98 | 220–222 | 221 | 266 () | 2.0193 | | CMRN 4 | C11H6Br2O3 (343) | 95 | 204–206 | 205 | 344 () | 2.2723 | | CMRN 5 | C11H6BrClO3 (299) | 94 | 180–182 | 181 | 300 () | 2.1223 | | CMRN 6 | C11H7ClO3 (222) | 95 | 218–220 | 219 | 223 () | 1.8693 | | CMRN 7 | C12H7BrN2O2S (321) | 87 | 210–212 | 211 | 322 () | 2.6992 |
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All of the products were characterized by spectral and physical data.
bYields were on isolated basis.
was calculated using ChemBioDraw Ultra 13.0 v.
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