The Scientific World Journal / 2014 / Article / Fig 5

Research Article

RNAi-Mediated Knockdown of IKK1 in Transgenic Mice Using a Transgenic Construct Containing the Human H1 Promoter

Figure 5

Most H1-IKK1-siRNA transgenic mice showed delayed hair follicle regrowth and hair follicle anomalies after depilation. (a) Slight (left) and severe (right) delay in the regrowth of hair follicles 11 days after depilation in transgenic mice. (b) Hematoxylin and eosin staining of skin histological sections. Morphological alterations in hair follicles of transgenic mice (black arrows) and dermal melanin deposition (red arrowheads) are shown. Bar: 80 μm.

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