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The Scientific World Journal
Volume 2014 (2014), Article ID 215084, 8 pages
http://dx.doi.org/10.1155/2014/215084
Research Article

Evaluation of Antioxidant and DNA Damage Protection Activity of the Hydroalcoholic Extract of Desmostachya bipinnata L. Stapf

1Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Bhopal, Bhopal, Madhya Pradesh 462023, India
2Department of Pharmacology, Faculty of Pharmaceutical Sciences, Bharat Institute of Technology, Hyderabad, Andhra Pradesh 501510, India

Received 31 August 2013; Accepted 24 October 2013; Published 19 January 2014

Academic Editors: G. M. Pacifici and D. Parolaro

Copyright © 2014 Upendarrao Golla and Solomon Sunder Raj Bhimathati. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. U. Golla, A. K. Kumar, and B. Solomon Suder Raj, “Assessment of antioxidant and hypnotic activity of unani formulation arq gulab,” Pharmacologyonline, vol. 1, pp. 930–941, 2011. View at Google Scholar · View at Scopus
  2. M. S. Rawat and R. Shankar, “Distribution status of medicinal plants conservation in arunachal pradesh with special reference to national medicinal plants board,” BMEBR, vol. 24, pp. 1–11, 2003. View at Google Scholar
  3. S. Sood, S. Bansal, A. Muthuraman, N. S. Gill, and M. Bali, “Therapeutic potential of Citrus medica L. peel extract in carrageenan induced inflammatory pain in rat,” Research Journal of Medicinal Plant, vol. 3, no. 4, pp. 123–133, 2009. View at Publisher · View at Google Scholar · View at Scopus
  4. M. R. Khan, M. Kihara, and A. D. Omoloso, “Antimicrobial activity of the alkaloidal constituents of the root bark of Eupomatia laurina,” Pharmaceutical Biology, vol. 41, no. 4, pp. 277–280, 2003. View at Publisher · View at Google Scholar · View at Scopus
  5. O. Potterat, “Antioxidants and free radical scavengers of natural origin,” Current Organic Chemistry, vol. 1, no. 4, pp. 415–440, 1997. View at Google Scholar · View at Scopus
  6. A. V. Audipudi and V. C. Bhaskar, “Antioxidative and antimicrobial activity of methanol and chloroform extracts of Gmelina arborea roxb,” International Journal of Biotechnology and Biochemistry, vol. 6, pp. 139–144, 2010. View at Google Scholar
  7. J. Kinsella, E. Frankel, B. German, and J. Kanner, “Possible mechanisms for the protective role of antioxidants in wine and plant foods,” Food Technology, vol. 47, pp. 85–89, 1993. View at Google Scholar
  8. N. S. Gill, J. Bajwa, K. Dhiman et al., “Evaluation of therapeutic potential of traditionally consumed Cucumis melo seeds,” Asian Journal of Plant Sciences, vol. 10, no. 1, pp. 86–91, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. V. V. Sivaranjan and B. Indira, Ayurvedic Drugs and Their Plant Sources, Oxford & IBH Publishing, New Delhi, India, 1994.
  10. S. G. Joshi, Medicinal Plants, Oxford & IBH Publishing, New Delhi, India, 2003.
  11. K. R. Kirtikar and B. D. Basu, Indian Medicinal Plants, International Book Distributors Book Sellerors and Publishers, Dehradun, India, 4th edition, 1918.
  12. M. S. Hifnawy, H. H. Ammar, S. A. Kenawy, M. E. Zaki, A. K. Yossef, and A. S. Awaad, “Phytochemical and biological studies on alkaloidal content of some allergy producing plants growing in Egypt,” Bulletin of Faculty of Pharmacy, Cairo University, vol. 37, pp. 107–117, 1999. View at Google Scholar
  13. S. A. Amani, H. M. Nawal, J. M. Derek, and A. S. Gamal, “Anti-ulcerogenic activity of extract and some isolated flavonoids from Desmostachya bipinnata (L.) Stapf,” Records of Natural Products, vol. 2, pp. 76–82, 2008. View at Google Scholar
  14. M. A. Ramadan and N. A. Safwat, “Antihelicobacter activity of a flavonoid compound isolated from Desmostachya bipinnata,” Australian Journal of Basic and Applied Sciences, vol. 3, no. 3, pp. 2270–2277, 2009. View at Google Scholar · View at Scopus
  15. S. Shrestha, H. N. Lyu, J. H. Park et al., “Sterols from the leafy culms of Desmostachya bipinnata,” Chemistry of Natural Compounds, vol. 47, no. 5, pp. 852–853, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. K. K. Ashok, S. Sharvanee, P. Jitendra, and C. Ram Kumar, “Chemical composition and antimicrobial activity of the essential oil of Desmostachya bipinnata linn,” International Journal of Phytomedicine, vol. 2, pp. 436–439, 2010. View at Google Scholar
  17. S. Panda, N. S. K. Choudhury, V. J. Patro, D. K. Pradhan, and G. K. Jan, “Analgesic, antipyretic and antiinflammatory effect of the whole plant extract of Desmostachya bipinnata stapf (poaceae) in albino rats,” Drug Invention Today, vol. 1, pp. 150–153, 2009. View at Google Scholar
  18. M. M. Hegde, K. Lakshman, K. Girija, B. A. Kumar, and V. Lakshmiprasanna, “Assessment of antidiarrhoeal activity of Desmostachya bipinnata L. (Poaceae) root extracts,” Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas, vol. 9, no. 4, pp. 312–318, 2010. View at Google Scholar · View at Scopus
  19. R. Bajwa, S. Riaz, and A. Javaid, “Antifungal activity of allelopathic plant exctracts II: in vitro control of Fusarium moniliforme and F. oxysporum by aqueous extracts of four allelopathic grasses,” in Proceedings of the 3rd National Conference of Plant Pathology, pp. 59–69, Islamabad, Pakistan, October 2002.
  20. S. Panda, N. S. K. Choudhury, B. R. Behera, S. K. Mahapatra, and B. C. Behera, “Study of antifungal activity of Desmostachya bipinnata,” Journal of Teaching and Research in Chemistry, vol. 15, pp. 47–49, 2008. View at Google Scholar
  21. H. Hashmi and A. Rashid, “Isolation of fungi from roots of Parthenium hysterophorus and Desmostachya bipinnata and antibacterial activity of their root extracts,” Journal of Biological Sciences, vol. 1, pp. 350–351, 2001. View at Publisher · View at Google Scholar
  22. S. Shrestha, J. H. Park, D. Y. Lee et al., “A new xanthene from Desmostachya bipinnata (L.) stapf inhibits signal transducer and activator of transcription 3 (STAT3) and low-density lipoprotein-oxidation,” Journal of Applied Biological Chemistry, vol. 54, no. 2, pp. 308–311, 2011. View at Publisher · View at Google Scholar · View at Scopus
  23. R. Sultana and M. S. Wagan, “The effect of food plants on the growth rate, fecundity and survivability of grasshopper Hieroglyphus nigrorepletus I. Bolivar (orthoperta: Acrididae) a major paddy pest in Pakistan,” Journal of Biological Sciences, vol. 7, no. 7, pp. 1282–1286, 2007. View at Google Scholar · View at Scopus
  24. U. Golla, P. K. Gajam, A. R. Mohammad, K. A. Kumar, and B. S. S. Raj, “Assessment of bioactivity of Desmostachya bipinnata (L.) Stapf using brine shrimp (artemia salina) lethality assay,” Pharmacologyonline, vol. 3, pp. 982–990, 2011. View at Google Scholar
  25. C. K. Kokate, A. P. Purohit, and S. B. Gokhale, Pharmacognosy, Nirali Prakashan, New Delhi, India, 2004.
  26. K. R. Khandelwal, Practical Pharmacognosy, Nirali Prakashan, New Delhi, India, 2006.
  27. I. Gülçin, H. A. Alici, and M. Cesur, “Determination of in vitro antioxidant and radical scavenging activities of propofol,” Chemical and Pharmaceutical Bulletin, vol. 53, no. 3, pp. 281–285, 2005. View at Publisher · View at Google Scholar · View at Scopus
  28. J. C. Lee, H. R. Kim, J. Kim, and Y. S. Jang, “Antioxidant property of an ethanol extract of the stem of Opuntia ficus-indica var. saboten,” Journal of Agricultural and Food Chemistry, vol. 50, no. 22, pp. 6490–6496, 2002. View at Publisher · View at Google Scholar · View at Scopus
  29. P. K. Wilmsen, D. S. Spada, and M. Salvador, “Antioxidant activity of the flavonoid hesperidin in chemical and biological systems,” Journal of Agricultural and Food Chemistry, vol. 53, no. 12, pp. 4757–4761, 2005. View at Publisher · View at Google Scholar · View at Scopus
  30. C. Dani, D. Bonatto, M. Salvador, M. D. Pereira, J. A. P. Henriques, and E. Eleutherio, “Antioxidant protection of resveratrol and catechin in Saccharomyces cerevisiae,” Journal of Agricultural and Food Chemistry, vol. 56, no. 11, pp. 4268–4272, 2008. View at Publisher · View at Google Scholar · View at Scopus
  31. M. D. Pereira, R. S. Herdeiro, P. N. Fernandes, E. C. A. Eleutherio, and A. D. Panek, “Targets of oxidative stress in yeast sod mutants,” Biochimica et Biophysica Acta, vol. 1620, no. 1–3, pp. 245–251, 2003. View at Publisher · View at Google Scholar · View at Scopus
  32. M. J. S. Miller, H. Sadowska-Krowicka, S. Chotinaruemol, J. L. Kakkis, and D. A. Clark, “Amelioration of chronic ileitis by nitric oxide synthase inhibition,” Journal of Pharmacology and Experimental Therapeutics, vol. 264, no. 1, pp. 11–16, 1993. View at Google Scholar · View at Scopus
  33. T. Nakayama, “Suppression of hydroperoxide-induced cytotoxicity by polyphenols,” Cancer Research, vol. 54, no. 7, 1994. View at Google Scholar · View at Scopus
  34. T. Nakayama, M. Yamada, T. Osawa, and S. Kawakishi, “Suppression of active oxygen-induced cytotoxicity by flavonoids,” Biochemical Pharmacology, vol. 45, no. 1, pp. 265–267, 1993. View at Publisher · View at Google Scholar · View at Scopus
  35. V. C. Sonntag, The Chemical Basis of Radiation Biology, Taylor & Francis, London, UK, 1987.
  36. T. Jun, Z. Liancai, and W. Bochu, “Effects of quercetin on DNA damage induced by copper ion,” International Journal of Pharmacology, vol. 3, no. 1, pp. 19–26, 2007. View at Google Scholar · View at Scopus
  37. B. W. Davies, M. A. Kohanski, L. A. Simmons, J. A. Winkler, J. J. Collins, and G. C. Walker, “Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli,” Molecular Cell, vol. 36, no. 5, pp. 845–860, 2009. View at Publisher · View at Google Scholar · View at Scopus
  38. K. Sakano, S. Oikawa, K. Hasegawa, and S. Kawanishi, “Hydroxyurea induces site-specific DNA damage via formation of hydrogen peroxide and nitric oxide,” Japanese Journal of Cancer Research, vol. 92, no. 11, pp. 1166–1174, 2001. View at Google Scholar · View at Scopus
  39. E. Maltas and S. Yildiz, “Evaluation of phytochemicals and antioxidant activity of ginkgo biloba from Turkey,” Pharmacologia, vol. 3, pp. 113–120, 2012. View at Google Scholar
  40. Q. M. Anderson and K. R. Markham, Flavonoids: Chemistry, Biochemistry and Applications, Taylor & Francis, New York, NY, USA, 2006.
  41. A. D. Boveris, M. Galleano, and S. Puntarulo, “In vivo supplementation with Ginkgo biloba protects membranes against lipid peroxidation,” Phytotherapy Research, vol. 21, no. 8, pp. 735–740, 2007. View at Publisher · View at Google Scholar · View at Scopus