Pharmacological Correction of Stress-Induced Gastric Ulceration by Novel Small-Molecule Agents with Antioxidant Profile

Table 2

Influence of compounds 3 (group VI) and 4 (group VII) (1 mg/kg, IP, 30 min before WIRS) on the activity of antioxidant enzymes in homogenates of rats gastric mucosa (𝑛=6, M ± m).

Animals group	I	II	III	VI	VII
SOD; (units min^−1 mg protein^−1)	0.19 ± 0.01	0.09 ± 0.01**	0.10 ± 0.01**	0.13 ± 0.01^**#	0.12 ± 0.01**
Catalase; (nmol min^−1 mg protein^−1)	5.83 ± 0.66	10.85 ± 0.79**	9.48 ± 0.56**	7.89 ± 0.46^#	8.50 ± 0.70^*#
Xanthine oxidase; (nmol min^−1 mg protein^−1)	70.00 ± 5.20	43.20 ± 2.60**	51.50 ± 2.50**	65.80 ± 2.10^##	63.20 ± 2.40^##

^∗𝑃<0.05, ^∗∗𝑃<0.01 compared to the intact control group I; ^#𝑃<0.05, ^##𝑃<0.01 compared to the stress control group II.